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Forschungsaktivitäten

2023

  • Parkinson’s Disease Biomarker Program
    Evaluation of novel EVaSyn-based biomarkers in a clinical study to assess their sensitivity and specificity as diagnostic and prognostic markers
  • IMPULSE 2: StIMulation of brain Plasticity to improve Upper Limb recovery from StrokE.
    A prospective pilot study (case series) to assess efficacy and safety of neuroplastic intervention by Cerebrolysin and atDCS on motor function recovery in subacute and chronic stroke patients, Ongoing investigation
  • ADVANCE – A Phase 2b, Multicenter, Randomized, Placebo- controlled, Double-blind Study to Assess the Safety and Efficacy of AD04 in Patients with Early Alzheimer’s Disease – ADVANCE, Ongoing study
  • Use of Nexstim Navigated Brain Therapy (NBT®) System in Treat classesment of Major Depressive Disorder , Register-Study, A. Winkler, E. Tadayon-Manssuri, NEXSTIM Plc.; Ongoing register study
  • AVANT Program: Assessing caregivers awareness and knowledge about neurorehabilitation of stroke patients, 2023; Ongoing investigation

 

Abgeschlossene Forschungsprojekte- und Kooperationen

Winkler, A. IMPULSE-Study, Stimulation of brain plasticity for improved arm recovery after a stroke: A prospective, multicenter, randomized, double-blind study to investigate the efficacy and safety of neuroplastic intervention using cerebrolysin and anodal transcranial direct current stimulation in the regeneration of motor functions in subacute and chronic stroke patients, EudraCT Number: 2019- 001799-12; Prematurely ended for pandemic and strategic reasons, March, 2022

Pohl J, Held JPO, Verheyden G, Alt Murphy M, Engelter s, Flöel A, Keller T, Kwakkel G, Nef T, Ward N,L uft AR and Veerbeek JM (2020) Consensus-Based Core Set of Outcome Measures for Clinical Motor Rehabilitation After Stroke –A Delphi Study. Front. Neurol. 202011:875

Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS) “NAVIGATE ESUS”, NEJM 5. 2018

The Changing Landscape for Stroke Prevention in AF, Findings From the GLORIA-AF Registry Phase 2 Journal of the American College of Cardiology; Volume 69, Issue 7, February 2017

Defining ‘Advanced’ Parkinson’s Disease in Clinical Practice: Results from the Austrian Full Analysis set of the OBSERVE-PD Study, a Cross-Sectional Observation Study of 2615 Patients. ÖPG, 2017

Advanced’ Parkinson’s disease characteristics in clinical practice: results from the OBSERVE- PD study, a cross-sectional observational study of 2615 patients Neurology, April 18, 2017; 88 (P6.0O1, 16 Supplement)

XANTUS: a real-world, prospective, observational study of patients treated with rivaroxaban for stroke prevention in atrial fibrillation; European Heart Journal, Volume 37, 7, April 2016

Thrombozyten als mögliches diagnostisches Ziel für neurodegenerative Erkrankungen. Substudie: Biochemische und genetische Verifikation der charakteristischen Veränderungen bei Alzheimerdemenz. Med.Uni. Wien Institut für Physiologie Zentrum f. Biomolekulare Medizin und Pharmakologie. M. Zellner, A. Winkler 2015